About us
Learn how GA4GH helps expand responsible genomic data use to benefit human health.
RNAget
Provides a common set of communication channels to efficiently retrieve RNA data of interest
The human body contains thousands of genes that support biological activities, from initiating processes like digestion to fighting off illness. To study gene expression, researchers use RNA sequencing — a powerful technology that captures gene activity levels based on the amount of RNA present in a cell. RNA sequencing experiments, however, require anywhere between 15 to 200 million RNA segments per biological sample. Such experiments can produce massive and complex files that are challenging to parse through and difficult to manage at scale. Developed by the GA4GH Large Scale Genomics (LSG) Work Stream, the RNAget API provides a common set of communication channels that allows researchers to efficiently retrieve RNA data of interest.
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Benefits
- Retrieves RNA data of interest, saving time and disk storage space
- Enables interoperability and harmonisation with other institutions through common RNA data structures
Target users
Researchers
Image summary: Learn how RNAget can help researchers retrieve a specific portion of RNA sequencing data for analysis.
THEME
CATEGORY
TYPE
STATUS
Work Stream
LATEST VERSION
Product Leads
- Sean Upchurch
- Emilio Palumbo
Staff Contact
Tools & Platforms
Community resources
Dive deeper into this product! RNAget describes a common set of endpoints to search and retrieve processed RNA data. Currently, the RNAget API allows for the retrieval of four data types: expression-level data based on a gene of interest; data from specific genomic coordinates; project-related information; and study-related information. The RNAget API allows the requester to specify a slice of the overall matrix for delivery — helping reduce the amount of data to transfer, and focusing data mining efforts. For the API to work seamlessly, the specification includes a testing application for servers to implement, ensuring compliance with the RNAget API.
Date
Version
Date
Title
15 Dec 2023
14 Sep 2023
11 Mar 2023
4 Jan 2022
8 Dec 2020
Canadian Distributed Infrastructure for Genomics (CanDIG)
ELIXIR Beacon
The Encyclopedia of DNA Elements (ENCODE)
EpiShare
Broad Institute of MIT and Harvard
Don't see your name? Get in touch:
- Jeremy Adams
DNAstack - Guillaume Bourque
McGill University / Université McGill - David Bujold
McGill University / Université McGill - Romain Gregoire
Canadian Centre for Computational Genomics - Roderic Guigo
Centre for Genomic Regulation - Ben Hitz
Stanford University - Emilio Palumbo
Centre for Genomic Regulation - Emilio Righi
Centre for Genomic Regulation - Sean Upchurch
California Institute of Technology - Andy Yates
EMBL's European Bioinformatics Institute (EBI) - Zhenyu Zhang
University of Chicago
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Catch up with all news and articles associated with RNAget.
